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Keywords: EGFR inhibitor
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Journal Articles
In collection:
Cancer
Adam D. Pfefferle, David B. Darr, Benjamin C. Calhoun, Kevin R. Mott, Jeffrey M. Rosen, Charles M. Perou
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (7): dmm037192.
Published: 5 July 2019
... extend this initial observation and show that Wnt1-Early Ex tumors exhibit high expression of canonical Wnt, non-canonical Wnt, and EGFR signaling pathway signatures. Therapeutically, Wnt1-Early Ex tumors showed a dynamic reduction in tumor volume when treated with an EGFR inhibitor. Wnt1-Early Ex tumors...
Includes: Supplementary data
