... medium provided that the original work is properly attributed. Summary: This article reviews and analyzes the available preclinical models for five common neonatal diseases to direct therapeutic development in these areas of high unmet medical need. Drug development Neonatal Nonclinical...

.... Translational research Neuromuscular disease Therapy Drug development Agence Nationale de la Recherche TREATSPG11 Be Est Projets d'Avenir, PIA-3 CoDyn101 Genetic diagnosis for neuromuscular disorders has rapidly improved over the past 20 years. This is due in large part...

... of genetically engineered mouse models (GEMMs), the development of new therapies for pancreatic cancer is still hampered by a lack of reliable and predictive preclinical animal models for this disease. Preclinical models are vitally important for assessing therapies in the first stages of the drug development...