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1-2 of 2
Keywords: Doxorubicin
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Journal Articles
In collection:
Human Genetic Disease
Bernhard N. Bohnert, Irene Gonzalez-Menendez, Thomas Dörffel, Jonas C. Schneider, Mengyun Xiao, Andrea Janessa, M. Zaher Kalo, Birgit Fehrenbacher, Martin Schaller, Nicolas Casadei, Kerstin Amann, Christoph Daniel, Andreas L. Birkenfeld, Florian Grahammer, Lahoucine Izem, Edward F. Plow, Leticia Quintanilla-Martinez, Ferruh Artunc
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (9): dmm049038.
Published: 15 September 2021
... Quintanilla-Martinez; Ferruh Artunc ABSTRACT Susceptibility to doxorubicin-induced nephropathy (DIN), a toxic model for the induction of proteinuria in mice, is related to the single-nucleotide polymorphism (SNP) C6418T of the Prkdc gene encoding for the DNA-repair enzyme DNA-PKcs. In addition, plasminogen...
Journal Articles
Cécile Voisset, Chrysoula Daskalogianni, Marie-Astrid Contesse, Anne Mazars, Hratch Arbach, Marie Le Cann, Flavie Soubigou, Sébastien Apcher, Robin Fåhraeus, Marc Blondel
Journal:
Disease Models & Mechanisms
Dis Model Mech (2014) 7 (4): 435–444.
Published: 1 April 2014
... by the major histocompatibility complex (MHC) class I pathway. Here we establish a yeast-based assay for monitoring GAr-dependent inhibition of translation. Using this assay we identify doxorubicin (DXR) as a compound that specifically interferes with the GAr effect on translation in yeast. DXR targets...
Includes: Supplementary data
