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Keywords: Dopaminergic neurons
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Journal Articles

A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease

Open Access
In collection:
Advanced in vitro models , Neurodegenerative Disorders
Zhao-Feng Li, Lei Cui, Mi-Mi Jin, Dong-Yan Hu, Xiao-Gang Hou, Shu-Shu Liu, Xiong Zhang, Jian-Hong Zhu
Journal: Disease Models & Mechanisms
Dis Model Mech (2022) 15 (3): dmm049125.
https://doi.org/10.1242/dmm.049125
Published: 8 March 2022
... of Parkinson's disease (PD), which recapitulates α-synuclein pathologies in human cells and could be used to investigate PD mechanisms and screen drugs. Parkinson's disease 3D modeling α-Synuclein Lewy body Dopaminergic neurons Zhejiang Provincial Natural Science Foundation http://dx.doi.org...
View articletitled, A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease
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Includes: Supplementary data
Journal Articles

A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity

Open Access
Subha Bakthavatsalam, Shreya Das Sharma, Mahendra Sonawane, Vatsala Thirumalai, Ankona Datta
Journal: Disease Models & Mechanisms
Dis Model Mech (2014) 7 (11): 1239–1251.
https://doi.org/10.1242/dmm.016683
Published: 1 November 2014
... permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Zebrafish Manganism Mechanotransduction Fictive motor patterns Dopaminergic neurons Manganese (manganese ion; referred to here as Mn) plays an important role...
View articletitled, A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity
Open the PDF for A zebrafish model of manganism reveals reversible and treatable symptoms that are independent of neurotoxicity in another window
Includes: Supplementary data