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Keywords: Disease models
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Journal Articles
Dis Model Mech (2019) 12 (9): dmm040360.
Published: 6 September 2019
... summarize the last 20 years of research in zebrafish models for hematopoietic disorders, highlighting how these models were created and are being applied for translational research. Disease models Hematopoiesis Blood disorders Leukemia Immunodeficiency Bone marrow failure syndrome Swiss...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2019) 12 (3): dmm039370.
Published: 7 March 2019
...E. Elizabeth Patton; David M. Tobin ABSTRACT Five years after the launch of the Disease Models & Mechanisms (DMM) Special Issue on zebrafish as a disease model, the field has progressed significantly. Zebrafish have been used to precisely model human genetic variants, to unpick the mechanisms...
Journal Articles
Dis Model Mech (2018) 11 (3): dmm032839.
Published: 12 March 2018
.../cpbi.27 Bello , S. M. , Richardson , J. E. , Davis , A. P. , Wiegers , T. C. , Mattingly , C. J. , Dolan , M. E. , Smith , C. L. , Blake , J. A. and Eppig , J. T. ( 2012 ). Disease model curation improvements at Mouse Genome Informatics . Database   2012...
Journal Articles
Dis Model Mech (2018) 11 (1): dmm030783.
Published: 22 January 2018
.... Disease models Genetic modification Pig Swine Deutsche Forschungsgemeinschaft 10.13039/501100001659 SCHN 971/3-2 Dr. Mildred Scheel Stiftung für Krebsforschung 111902 Studienstiftung des Deutschen Volkes 10.13039/501100004350 European Cooperation...
Journal Articles
Dis Model Mech (2016) 9 (8): 823–838.
Published: 1 August 2016
.... Chaperone Co-chaperone Chaperome Proteostasis network Protein-misfolding disease Disease models Chaperones and co-chaperones, collectively referred to as the chaperome ( Box 1 ), work together in a network of macromolecular protein folding, refolding and degradation machines. These machines...
Journal Articles
Journal Articles
Dis Model Mech (2015) 8 (11): 1349–1360.
Published: 1 November 2015
... to elucidate these complex regulatory mechanisms. In this Review, we discuss recent advances in our understanding of hypoxia and HIFs in disease that have emerged from studies of zebrafish disease models. Findings from such models identify HIF as an integral player in the disease processes. They also highlight...
Journal Articles
Dis Model Mech (2014) 7 (7): 777–784.
Published: 1 July 2014
...://creativecommons.org/licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Disease models Genetics Mycobacterium Pathogenesis Tuberculosis Zebrafish Since arising as a human pathogen an estimated...