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1-6 of 6
Keywords: Disease modeling
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Journal Articles
In collection:
Developmental Disorders
Eleonora Maino, Ori Scott, Samar Z. Rizvi, Wing Suen Chan, Shagana Visuvanathan, Youssif Ben Zablah, Hongbin Li, Ameet S. Sengar, Michael W. Salter, Zhengping Jia, Janet Rossant, Ronald D. Cohn, Bin Gu, Evgueni A. Ivakine
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (7): dmm050528.
Published: 23 July 2024
.... MECP2 duplication syndrome IRAK1 Disease modeling Intellectual disability Interferon Mouse model Reverse Rett Research Fund Canadian Institutes of Health Research http://dx.doi.org/10.13039/501100000024 FDN-143334 Ontario Ministry of Health and Long-Term Care...
Includes: Supplementary data
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (7): dmm050947.
Published: 8 July 2024
... provided that the original work is properly attributed. Summary: The ISSCR provides comprehensive guidelines and standards for using human stem cells in biomedical research. Here, we discuss how and why these should be incorporated in disease modeling research. Disease modeling ISSCR Stem...
Journal Articles
In collection:
C. elegans as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (3): dmm050412.
Published: 2 April 2024
...Rewayd Shalash; Mor Levi-Ferber; Coral Cohen; Amir Dori; Chaya Brodie; Sivan Henis-Korenblit ABSTRACT Reliable disease models are critical for medicine advancement. Here, we established a versatile human disease model system using patient-derived extracellular vesicles (EVs), which transfer...
Includes: Supplementary data
Journal Articles
Martyna M. Grochowska, Federico Ferraro, Ana Carreras Mascaro, Domenico Natale, Amber Winkelaar, Valerie Boumeester, Guido J. Breedveld, Vincenzo Bonifati, Wim Mandemakers
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (6): dmm049980.
Published: 23 June 2023
... from human pluripotent stem cells of cortical neurons of the superficial layers amenable to psychiatric disease modeling and high-throughput drug screening . Transl. Psychiatry 3 , e294 . 10.1038/tp.2013.71 Bonni , A. , Sun , Y. , Nadal-Vicens , M. , Bhatt , A. , Frank...
Includes: Supplementary data
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (8): dmm049010.
Published: 9 August 2021
... the small model organisms that excel in rare disease modeling is the nematode Caenorhabditis elegans . With a staggering breadth of research tools, C. elegans provides an ideal system in which to study human disease. Molecular and cellular processes can be easily elucidated, assayed and altered in ways...
Journal Articles
In collection:
Perspectives on Translational Research
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (8): dmm041699.
Published: 20 August 2019
...Antonis K. Hatzopoulos ABSTRACT In the decade since Disease Models & Mechanisms was launched, the emergence of Big Data as the main foundation of biological information is having a profound effect on how we do research and it has provoked some interesting questions. Is Big Data exploration...