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1-5 of 5
Keywords: Diet
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Journal Articles
In collection:
Cancer Metabolism
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (9): dmm050814.
Published: 16 September 2024
... reciprocally affects tumor metabolism and biology. Acidosis Diet Hypoxia Lipid metabolism Nutrient deprivation Tumor microenvironment References Ackerman , D. , Tumanov , S. , Qiu , B. , Michalopoulou , E. , Spata , M. , Azzam , A. , Xie , H. , Simon , M. C...
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (1): dmm049671.
Published: 20 January 2023
..., we generated a zebrafish system that can be used as a platform for studying these factors. We studied how germline overexpression of Agrp along with a high-fat diet affects melanomas dependent on BRAF V600E and loss of p53. This revealed an increase in tumor incidence and area in male, but not female...
Includes: Supplementary data
Journal Articles
In collection:
Metabolic Disorders
Masayoshi Ko, Kenya Kamimura, Takashi Owaki, Takuro Nagoya, Norihiro Sakai, Itsuo Nagayama, Yusuke Niwa, Osamu Shibata, Chiyumi Oda, Shinichi Morita, Atsushi Kimura, Ryosuke Inoue, Toru Setsu, Akira Sakamaki, Takeshi Yokoo, Shuji Terai
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (3): dmm048922.
Published: 28 March 2021
... defined L-amino-acid and high-fat diet-fed mice with or without blockades of autonomic nerves from the liver. Blockade of the neural signal from the liver to the gut in these NAFLD mice models ameliorated the progression of liver weight, hepatic steatosis and fibrosis by modulating serotonin expression...
Includes: Supplementary data
Journal Articles
Divya Krishnamoorthy, Robert C. Hoy, Devorah M. Natelson, Olivia M. Torre, Damien M. Laudier, James C. Iatridis, Svenja Illien-Jünger
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (12): dmm036012.
Published: 18 December 2018
... at high heat. Collagen-rich IVDs are particularly susceptible to AGE accumulation due to their slow metabolic rates, yet it is unclear whether dietary AGEs can cross the endplates to accumulate in IVDs. A dietary mouse model was used to test the hypothesis that chronic consumption of high AGE diets...
Includes: Supplementary data
Journal Articles
In collection:
Tools and Resources for Mouse Studies
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (10): dmm035360.
Published: 1 October 2018
... environments affect phenotypes is critical for the development of models of human disease. Husbandry Diet Environment Stress Mouse models Human National Institutes of Health 10.13039/100000002 R01 AR049288 CA089713 R21 AR063781 “ Little boxes, little boxes, little boxes all...