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Journal Articles

Vitamin D deficiency in the Apc Pirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective

Open Access
In collection:
Rat as a Disease Model
Amy A. Irving, Elizabeth G. Duchow, Lori A. Plum, Hector F. DeLuca
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (3): dmm032300.
https://doi.org/10.1242/dmm.032300
Published: 7 March 2018
... and, in fact, increased tumor multiplicity in a dose-dependent manner. In the current study, we tested whether vitamin D deficiency plays a causative role in tumor development using two strains which differ in their susceptibility to intestinal tumorigenesis. In the colon, vitamin D deficiency did not increase...
View articletitled, Vitamin D deficiency in the Apc Pirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective
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Includes: Supplementary data