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Keywords: Danio rerio
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Journal Articles

Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

Open Access
In collection:
Zebrafish as a Disease Model
Yonghe Ding, Alexey V. Dvornikov, Xiao Ma, Hong Zhang, Yong Wang, Matthew Lowerison, Rene R. Packard, Lei Wang, Jun Chen, Yuji Zhang, Tzung Hsiai, Xueying Lin, Xiaolei Xu
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (10): dmm040154.
https://doi.org/10.1242/dmm.040154
Published: 1 October 2019
... is properly attributed. Summary: This study shows that adult bag3 knockout mutant zebrafish can be used as a model for DCM, and haploinsufficiency of mTOR is cardioprotective. Dilated cardiomyopathy BCL2-associated athanogene 3 mTOR Danio rerio American Heart Association...
View article titled, Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish
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Includes: Supplementary data
Journal Articles

Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish

Open Access
In collection:
Cancer , Rare Disease Translational Research , The RAS Pathway , Zebrafish as a Disease Model
Gianluca D'Agati, Elena María Cabello, Karl Frontzek, Elisabeth J. Rushing, Robin Klemm, Mark D. Robinson, Richard M. White, Christian Mosimann, Alexa Burger
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (7): dmm039545.
https://doi.org/10.1242/dmm.039545
Published: 16 July 2019
... selected for experimentation. The lines Tg(-2.7twhh:Gal4) and Tg(5xUAS:eGFP-HRASV12) have been previously described (Burger et al., 2014 ; Santoriello et al., 2010). Zebrafish (Danio rerio) were maintained, collected and staged principally as described (Kimmel et al., 1995 ; Westerfield, 2007...
View article titled, Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
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Includes: Supplementary data
Journal Articles

A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides

Open Access
Kerstin Voelz, Remi L. Gratacap, Robert T. Wheeler
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (11): 1375–1388.
https://doi.org/10.1242/dmm.019992
Published: 1 November 2015
... is properly attributed. Summary: We use zebrafish larval models to delineate the temporospatial patterns of innate immune responses to fungal infections with mucormycete spores. Zebrafish larva Danio rerio Mucormycosis Innate immune system Phagocytes Macrophages Neutrophils Mucor...
View article titled, A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides
Open the PDF for A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides in another window
Includes: Supplementary data