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Keywords: Danio rerio
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Journal Articles

Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

In collection:
Zebrafish as a Disease Model
Yonghe Ding, Alexey V. Dvornikov, Xiao Ma, Hong Zhang, Yong Wang, Matthew Lowerison, Rene R. Packard, Lei Wang, Jun Chen, Yuji Zhang, Tzung Hsiai, Xueying Lin, Xiaolei Xu
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (10): dmm040154.
https://doi.org/10.1242/dmm.040154
Published: 1 October 2019
... that the original work is properly attributed. Summary: This study shows that adult bag3 knockout mutant zebrafish can be used as a model for DCM, and haploinsufficiency of mTOR is cardioprotective. Dilated cardiomyopathy BCL2-associated athanogene 3 mTOR Danio rerio American Heart...
View article titled, Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish
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Includes: Supplementary data
Journal Articles

Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish

In collection:
Cancer , Rare Disease Translational Research , The RAS Pathway , Zebrafish as a Disease Model
Gianluca D'Agati, Elena María Cabello, Karl Frontzek, Elisabeth J. Rushing, Robin Klemm, Mark D. Robinson, Richard M. White, Christian Mosimann, Alexa Burger
Journal: Disease Models & Mechanisms
Dis Model Mech (2019) 12 (7): dmm039545.
https://doi.org/10.1242/dmm.039545
Published: 16 July 2019
... could consequently attack a main pathway required for the initial transformation of native notochord cells towards chordoma. Zebrafish ( Danio rerio ) were maintained, collected and staged principally as described ( Kimmel et al., 1995 ; Westerfield, 2007 ) and in agreement with procedures...
View article titled, Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
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Includes: Supplementary data
Journal Articles

A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides

Kerstin Voelz, Remi L. Gratacap, Robert T. Wheeler
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (11): 1375–1388.
https://doi.org/10.1242/dmm.019992
Published: 1 November 2015
... lack of chemotactic potential of infectious spores in vivo and gained a better understanding of early events of a failed immune response leading to fatal mucormycosis as well as some mechanistic insight into disease dissemination. In recent years, the zebrafish ( Danio rerio ) larval model has...
View article titled, A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides
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Includes: Supplementary data