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Keywords: DNA repair
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Journal Articles
In collection:
Cancer Metabolism
Dis Model Mech (2024) 17 (8): dmm050775.
Published: 29 August 2024
... the causes and consequences of dNTP pool perturbations in cancer cells, together with their impact upon genome stability. Deoxynucleoside triphosphate (dNTP) metabolism Genome stability DNA repair Cancer Vetenskapsrådet http://dx.doi.org/10.13039/501100004359 2018-02114...
Journal Articles
Dis Model Mech (2022) 15 (5): dmm049424.
Published: 9 May 2022
... and skeletal muscle, resulting in both morphological and changes in gene expression ( Lodberg, 2021 ). In conclusion, we have shown for the first time that a model of attenuated DNA repair is associated with pathological cardiac remodelling and gene expression. However, a significant amount...
Includes: Supplementary data
Journal Articles
Journal Articles
Dis Model Mech (2018) 11 (1): dmm031930.
Published: 30 January 2018
... and central neurodegeneration, but our understanding of how expanded repeats drive neuronal loss is incomplete. Recent human genetic evidence implicates DNA repair pathways, especially mismatch repair, in modifying the onset and progression of CAG repeat diseases. Repair pathways might operate directly...