1-3 of 3
Keywords: Colon cancer
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Vitamin D deficiency in the Apc Pirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective

Open Access
In collection:
Rat as a Disease Model
Amy A. Irving, Elizabeth G. Duchow, Lori A. Plum, Hector F. DeLuca
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (3): dmm032300.
https://doi.org/10.1242/dmm.032300
Published: 7 March 2018
...Amy A. Irving; Elizabeth G. Duchow; Lori A. Plum; Hector F. DeLuca ABSTRACT Human studies have shown that individuals with colon cancer tend to have lower serum 25-hydroxy-vitamin D 3 [25(OH)D 3 ] levels compared with healthy controls, but whether this link is causative, a result of the disease...
View articletitled, Vitamin D deficiency in the Apc Pirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective
Open the PDF for Vitamin D deficiency in the Apc Pirc/+ rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective in another window
Includes: Supplementary data
Journal Articles

Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines

Open Access
Jingjing Ma, Jin Cheng, Yanping Gong, Ling Tian, Qian Huang
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (4): 385–391.
https://doi.org/10.1242/dmm.018887
Published: 1 April 2015
... a crucial role in the repopulation of colon cancer and pancreatic cancer cells. Cancer stem cells are classically resistant to conventional chemotherapy and radiation therapy through a variety of mechanisms, including the effects of tumor cell repopulation (Moncharmont et al., 2012). According...
View articletitled, Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines
Open the PDF for Downregulation of Wnt signaling by sonic hedgehog activation promotes repopulation of human tumor cell lines in another window
Journal Articles

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish

Open Access
Alexander J. Valvezan, Jian Huang, Christopher J. Lengner, Michael Pack, Peter S. Klein
Journal: Disease Models & Mechanisms
Dis Model Mech (2014) 7 (1): 63–71.
https://doi.org/10.1242/dmm.012625
Published: 1 January 2014
... and reproduction in any medium provided that the original work is properly attributed. APC Wnt mTOR mTORC1 Zebrafish Colon cancer Polyposis GSK-3 Colorectal cancer (CRC) is responsible for over 600,000 deaths annually worldwide (USCSW Group, 2013). Some 80% of sporadic CRCs result from...
View articletitled, Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish
Open the PDF for Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish in another window
Includes: Supplementary data