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Keywords: Cochlear development
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Journal Articles

Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model

Sen Chen, Le Xie, Kai Xu, Hai-Yan Cao, Xia Wu, Xiao-Xiang Xu, Yu Sun, Wei-Jia Kong
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (2): dmm033019.
https://doi.org/10.1242/dmm.033019
Published: 26 February 2018
... Connexin26 Cochlear development Gjb2 Hearing loss Summary: A reduction in connexin 26 before opening of the tunnel of Corti impedes microtubule formation in supporting cells, and this may lead to cochlear developmental abnormalities and deafness in the Gjb2 knockdown mouse model. © 2018...
View articletitled, Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model
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Includes: Supplementary data
Journal Articles

The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells

Andrew Parker, Sally H. Cross, Ian J. Jackson, Rachel Hardisty-Hughes, Susan Morse, George Nicholson, Emma Coghill, Michael R. Bowl, Steve D. M. Brown
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (12): 1555–1568.
https://doi.org/10.1242/dmm.023176
Published: 1 December 2015
..., multiple roles of MAP3K1 in cochlear development and correct auditory function. MAP3K1 Supernumerary outer hair cells Cochlear development Sensory hair cell survival Hearing loss The signalling pathways underlying epithelial sheet movements are well studied, and have identified...
View articletitled, The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells
Open the PDF for The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells in another window
Includes: Supplementary data