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Keywords: Cholesterol
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Journal Articles
Dis Model Mech (2021) 14 (10): dmm048929.
Published: 26 October 2021
... a novel form of intercellular communication, have been shown to influence the function/vulnerability of neurons in AD. Unlike neurons, the significance of exosomes derived from astrocytes remains unclear. In this study, we evaluated the significance of exosomes derived from U18666A-induced cholesterol...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2020) 13 (6): dmm042549.
Published: 24 June 2020
...Rebecca A. Anderson; Kevin T. Schwalbach; Stephanie R. Mui; Elizabeth E. LeClair; Jolanta M. Topczewska; Jacek Topczewski ABSTRACT Human disorders of the post-squalene cholesterol biosynthesis pathway frequently result in skeletal abnormalities, yet our understanding of the mechanisms involved...
Includes: Supplementary data
Journal Articles
In collection:
Metabolic Disorders
Dis Model Mech (2020) 13 (4): dmm042911.
Published: 06 April 2020
... that, even after 24 h, very little DiI could be detected in the mutant HLC, whereas robust fluorescence is detected in the corrected HLC at both 6 h and 24 h. When cellular cholesterol is depleted by statin and methyl-β-cyclodextrin, even at 6 h, neither FH nor corrected HLC showed a quantifiable change...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2014) 7 (2): 265–270.
Published: 01 February 2014
... results demonstrate that etv7 regulates the expression of the zebrafish lanosterol synthase ( lss ) gene, an essential gene in the cholesterol synthesis pathway. Furthermore, morpholino knockdown of etv7 leads to loss of hemoglobin-containing red blood cells, a phenotype that can be rescued by injection...
Includes: Supplementary data