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Keywords: Cholangiocarcinoma
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Journal Articles
In collection:
Cancer
Mireia Sueca-Comes, Elena Cristina Rusu, Jennifer C. Ashworth, Pamela Collier, Catherine Probert, Alison Ritchie, Marian Meakin, Nigel P. Mongan, Isioma U. Egbuniwe, Jesper Bøje Andersen, David O. Bates, Anna M. Grabowska
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (12): dmm050716.
Published: 13 December 2024
... formation and progression through dynamic interactions. Cholangiocarcinoma (CCA), a highly desmoplastic tumour, lacks early diagnostic biomarkers and has limited effective treatments owing to incomplete understanding of its molecular pathogenesis. Investigating the role of the TME in CCA progression could...
Includes: Supplementary data
Journal Articles
William B. Alexander, Wenjia Wang, Margaret A. Hill, Michael R. O'Dell, Luis I. Ruffolo, Bing Guo, Katherine M. Jackson, Nicholas Ullman, Scott C. Friedland, Matthew N. McCall, Ankit Patel, Nathania Figueroa-Guilliani, Mary Georger, Brian A. Belt, Christa L. Whitney-Miller, David C. Linehan, Patrick J. Murphy, Aram F. Hezel
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (6): dmm050358.
Published: 28 February 2024
...; Patrick J. Murphy; Aram F. Hezel ABSTRACT Cholangiocarcinoma (CCA) is a deadly and heterogeneous type of cancer characterized by a spectrum of epidemiologic associations as well as genetic and epigenetic alterations. We seek to understand how these features inter-relate in the earliest phase of cancer...
Includes: Supplementary data
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2018) 11 (8): dmm033050.
Published: 14 May 2018
...Gigin Lin; Kun-Ju Lin; Frank Wang; Tse-Ching Chen; Tzu-Chen Yen; Ta-Sen Yeh ABSTRACT Although gemcitabine plus cisplatin is the gold standard chemotherapy regimen for advanced cholangiocarcinoma, the response rate has been disappointing. This study aims to investigate a novel therapeutic regimen...
