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Keywords: Characterization
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Journal Articles
Dis Model Mech (2020) 13 (8): dmm044891.
Published: 27 August 2020
... an inducible, dominant-negative form of human UPF1 ( dnUPF1 ) to inhibit NMD in mouse tissues by different degrees, allowing us to examine the effects of global NMD inhibition in vivo . A thorough characterization of these mice indicated that expressing dnUPF1 at levels that promote relatively moderate...
Includes: Supplementary data
Journal Articles