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Keywords: Chaperonopathies
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Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2014) 7 (4): 421–434.
Published: 1 April 2014
... or ‘barcoded’ by a different set of HSPs that can rescue specific types of aggregation. Some of these ‘non-canonical’ HSPs have demonstrated effectiveness in vivo , in mouse models of protein-aggregation disease. Interestingly, several of these HSPs also cause diseases when mutated – so-called chaperonopathies...
