... defects in attentional control abilities. Collagen VI Mouse model Central nervous system Dopamine Prefrontal cortex Cognitive function Fondazione Cassa di Risparmio di Padova e Rovigo http://dx.doi.org/10.13039/100007479 Starting Grants 2015 Università degli Studi di...

... preclinical modelling of glioblastoma multiforme to understand its biology and develop therapies, with a focus on mammalian model systems. Central nervous system In vitro CRISPR/Cas9 Mouse Human Xenograft GBM Cancer Brain tumour Cancer Research UK 10.13039/501100000289 A19778...

... established, the role of this distinctive extracellular matrix component in the central nervous system, along with its links to human neurological and neurodegenerative disorders, remains an open field of investigation. In this Review, we summarize and discuss a number of recent findings related to collagen...

... virus (SINV), are vector-borne pathogens that cause acute illnesses in humans and are sometimes associated with neuropathies, especially in infants and elderly patients. Little is known about their mechanism of entry into the central nervous system (CNS), even for SINV, which has been used extensively...

... because of the early lethality of hemizygous-null animals. In this study, we evaluated the outcome of brain-specific Atrx deletion in heterozygous female mice. These mice exhibit a mosaic pattern of ATRX protein expression in the central nervous system attributable to the location of the gene on the X...

...Martin M. Herrmann; Silvia Barth; Bernhard Greve; Kathrin M. Schumann; Andrea Bartels; Robert Weissert ABSTRACT After encounter with a central nervous system (CNS)-derived autoantigen, lymphocytes leave the lymph nodes and enter the CNS. This event leads only rarely to subsequent tissue damage...