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Journal Articles

Identification of histone deacetylase inhibitors as neutrophil recruitment modulators in zebrafish using a chemical library screen

In collection:

Drug Discovery , Zebrafish as a Disease Model

Sijia Fan, Jinlong Jiang, Huan Zhang, Cuihong Wang, Shang Kong, Tingting Zhao, Ling Meng, Yang Liu, Jingjing Qin, Xiuqin Rong, Zhenting He, Qinke He, Ke He, Ketong Chen, Ling Lei, Xinyu Hai, Hong Nie, Chunguang Ren

Dis Model Mech (2023) 16 (10): dmm050056.

https://doi.org/10.1242/dmm.050056

Published: 13 October 2023

... Cell migration HDAC AR-42 National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809 32170766 8181101216 China Postdoctoral Science Foundation http://dx.doi.org/10.13039/501100002858 2021MD703921 Chongqing Municipal Science...

View article titled, Identification of histone deacetylase inhibitors as neutrophil recruitment modulators in zebrafish using a chemical library screen

Includes: Supplementary data

Journal Articles

Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation

In collection:

Developmental Disorders

Weizhuo Wang, Feiyang Li, Jing Wang, Zuimeng Liu, Meiyu Tian, Zhenhang Wang, Huirong Li, Jia Qu, Yu Chen, Ling Hou

Dis Model Mech (2023) 16 (8): dmm050210.

https://doi.org/10.1242/dmm.050210

Published: 29 August 2023

... but of increased migration to ectopic locations such as the cornea. In melanoblasts in vitro , Sufu knockdown replicated the increase in cell migration without affecting proliferation and was mediated by an increased level of phosphorylated-ERK brought about by a reduction in the levels of the repressor form...

View article titled, Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation

Includes: Supplementary data

Journal Articles

Abnormalities in the migration of neural precursor cells in familial bipolar disorder

Salil K. Sukumaran, Pradip Paul, Vishwesha Guttal, Bharath Holla, Alekhya Vemula, Harsimar Bhatt, Piyush Bisht, Kezia Mathew, Ravi K. Nadella, Anu Mary Varghese, Vijayalakshmi Kalyan, Meera Purushottam, Sanjeev Jain, ADBS Consortium, Reeteka Sud, Biju Viswanath

Dis Model Mech (2022) 15 (10): dmm049526.

https://doi.org/10.1242/dmm.049526

Published: 18 October 2022

... under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: Cell migration patterns are abnormal in neural...

View article titled, Abnormalities in the migration of neural precursor cells in familial bipolar disorder

Includes: Supplementary data

Journal Articles

Ccdc103 promotes myeloid cell proliferation and migration independent of motile cilia

Lauren G. Falkenberg, Sarah A. Beckman, Padmapriyadarshini Ravisankar, Tracy E. Dohn, Joshua S. Waxman

Dis Model Mech (2021) 14 (5): dmm048439.

https://doi.org/10.1242/dmm.048439

Published: 24 May 2021

... of motile cilia in zebrafish embryos, and that CCDC103 mutations underlying primary ciliary dyskinesia abrogate interactions with the microtubule-stabilizing protein SPAG6. CCDC103 Cell migration Microtubules Myeloid cells Primary ciliary dyskinesia Zebrafish Primary ciliary dyskinesia...

View article titled, Ccdc103 promotes myeloid cell proliferation and migration independent of motile cilia

Includes: Supplementary data

Journal Articles

Spz/Toll-6 signal guides organotropic metastasis in Drosophila

In collection:

Drosophila as a Disease Model

Ketu Mishra-Gorur, Daming Li, Xianjue Ma, Yanki Yarman, Lei Xue, Tian Xu

Dis Model Mech (2019) 12 (10): dmm039727.

https://doi.org/10.1242/dmm.039727

Published: 7 October 2019

...Ketu Mishra-Gorur; Daming Li; Xianjue Ma; Yanki Yarman; Lei Xue; Tian Xu ABSTRACT Targeted cell migration plays important roles in developmental biology and disease processes, including in metastasis. Drosophila tumors exhibit traits characteristic of human cancers, providing a powerful model...

View article titled, Spz/Toll-6 signal guides organotropic metastasis in Drosophila

Includes: Supplementary data

Journal Articles

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

In collection:

Drug Discovery , Zebrafish as a Disease Model

Margarita Parada-Kusz, Cristina Penaranda, Elliott J. Hagedorn, Anne Clatworthy, Anil V. Nair, Jonathan E. Henninger, Christoph Ernst, Brian Li, Raquel Riquelme, Humberto Jijon, Eduardo J. Villablanca, Leonard I. Zon, Deborah Hung, Miguel L. Allende

Dis Model Mech (2018) 11 (11): dmm034876.

https://doi.org/10.1242/dmm.034876

Published: 5 November 2018

... Beltman , J. B. , Marée , A. F. M. and de Boer , R. J. ( 2009 ). Analysing immune cell migration . Nat. Rev. Immunol. 9 , 789 - 798 . 10.1038/nri2638 Bertrand , J. Y. , Kim , A. D. , Teng , S. and Traver , D. ( 2008 ). CD41+ cmyb+ precursors colonize...

View article titled, Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

Includes: Supplementary data

Journal Articles

Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish

In collection:

Zebrafish as a Disease Model

Wenqing Zhou, Lingyan Cao, Jacob Jeffries, Xiaoguang Zhu, Christopher J. Staiger, Qing Deng

Dis Model Mech (2018) 11 (3): dmm033027.

https://doi.org/10.1242/dmm.033027

Published: 28 March 2018

... ), pharmacological mitochondria electron transport inhibition with rotenone, or metabolic switch ( Porporato et al., 2014 ), promotes cancer cell migration and invasion. Taken together, the physiological relevance of mitochondrial ROS levels and the dynamics of mitochondria networks are highly context dependent...

View article titled, Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish

Includes: Supplementary data

Journal Articles

Musculocontractural Ehlers–Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin

Nadège Gouignard, Marco Maccarana, Ina Strate, Kristoffer von Stedingk, Anders Malmström, Edgar M. Pera

Dis Model Mech (2016) 9 (6): 607–620.

https://doi.org/10.1242/dmm.024661

Published: 1 June 2016

... transition (EMT) and reduces the extent of NC cell migration, which leads to a decrease in NC-derived craniofacial skeleton, melanocytes and dorsal fin structures. Transplantation experiments demonstrate a tissue-autonomous role for DS-epi1 in cranial NC cell migration in vivo . Cranial NC explant and single...

View article titled, Musculocontractural Ehlers–Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin

Includes: Supplementary data

NARROW

Identification of histone deacetylase inhibitors as neutrophil recruitment modulators in zebrafish using a chemical library screen

Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation

Abnormalities in the migration of neural precursor cells in familial bipolar disorder

Ccdc103 promotes myeloid cell proliferation and migration independent of motile cilia

Spz/Toll-6 signal guides organotropic metastasis in Drosophila

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish

Musculocontractural Ehlers–Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin

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