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1-3 of 3
Keywords: Cell death
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Journal Articles
In collection:
Infectious disease biology
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (7): dmm049414.
Published: 8 July 2022
...Dominik Brokatzky; Serge Mostowy ABSTRACT Pyroptosis, a regulated form of pro-inflammatory cell death, is characterised by cell lysis and by the release of cytokines, damage- and pathogen-associated molecular patterns. It plays an important role during bacterial infection, where it can promote...
Journal Articles
In collection:
Metabolic Disorders
Eva Baquedano, Emma Burgos-Ramos, Sandra Canelles, Agueda González-Rodríguez, Julie A. Chowen, Jesús Argente, Vicente Barrios, Angela M. Valverde, Laura M. Frago
Journal:
Disease Models & Mechanisms
Dis Model Mech (2016) 9 (5): 573–583.
Published: 1 May 2016
... cell death and activation of caspase-8 and -3 in the hypothalamus. Regulators of apoptosis such as FADD, Bcl-2, Bcl-xL and p53 were also increased, whereas p-IκB and c-FLIP L were decreased. This was accompanied by increased levels of Nox-4 and catalase, enzymes involved in oxidative stress. In summary...
Journal Articles
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (7): 669–677.
Published: 1 July 2015
... was determined. Motor function of surviving adults was examined with a climbing assay, and longevity was assessed by measuring lifespan. Neuronal cell death was assayed by using immunohistochemistry in adult brains. We also tested the sensitivity at different developmental stages by irradiating larvae at various...