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Keywords: Cdk8
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Journal Articles
In collection:
Drosophila as a Disease Model
Journal:
Disease Models & Mechanisms
Dis Model Mech (2022) 15 (11): dmm049650.
Published: 14 November 2022
... that control the transcription of lipogenic and cholesterogenic genes, but the mechanisms modulating SREBP-dependent transcription are still not fully understood. We previously reported that CDK8, a subunit of the transcription co-factor Mediator complex, phosphorylates SREBP at a conserved threonine residue...
Includes: Supplementary data