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Keywords: Cardiovascular Disease
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Journal Articles
Identifying links between cardiovascular disease and insomnia by modeling genes from a pleiotropic locus
Open AccessFarah Abou Daya, Torrey Mandigo, Lily Ober, Dev Patel, Matthew Maher, Suraj Math, Cynthia Tchio, James A. Walker, Richa Saxena, Girish C. Melkani
Journal:
Disease Models & Mechanisms
Dis Model Mech (2025) 18 (5): dmm052139.
Published: 6 May 2025
...Farah Abou Daya; Torrey Mandigo; Lily Ober; Dev Patel; Matthew Maher; Suraj Math; Cynthia Tchio; James A. Walker; Richa Saxena; Girish C. Melkani ABSTRACT Insomnia symptoms double the risk of cardiovascular disease (CVD), yet shared genetic pathways remain unclear. Genome-wide association studies...
Includes: Supplementary data
Journal Articles
In collection:
Heart Disease
Seakcheng Lim, Melissa M. Mangala, Mira Holliday, Henrietta Cserne Szappanos, Samantha Barratt-Ross, Serena Li, Jordan Thorpe, Whitney Liang, Ginell N. Ranpura, Jamie I. Vandenberg, Christopher Semsarian, Adam P. Hill, Livia C. Hool
Journal:
Disease Models & Mechanisms
Dis Model Mech (2024) 17 (8): dmm050407.
Published: 27 August 2024
... conduction slowing, increased spatial dispersion of repolarization and reduced expression of some rhythmonome proteins, suggesting a biophysical basis for arrhythmia in hypertrophic cardiomyopathy. Arrhythmia Cardiovascular disease Electrophysiology Stem cells National Health and Medical...
Includes: Supplementary data
Journal Articles
Saba Naghipour, Joshua J. Fisher, Anthony V. Perkins, Jason N. Peart, John P. Headrick, Eugene F. Du Toit
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (5): dmm049975.
Published: 15 May 2023
...Saba Naghipour; Joshua J. Fisher; Anthony V. Perkins; Jason N. Peart; John P. Headrick; Eugene F. Du Toit ABSTRACT Trimethylamine-N-oxide (TMAO) is an end-product of gut microbiome metabolism linked to cardiovascular disease (CVD). However, precise cardiovascular influences of the TMAO...
Includes: Supplementary data
Journal Articles
In collection:
Metabolic Disorders
Amélie Bacle, Linette Kadri, Spiro Khoury, Romain Ferru-Clément, Jean-François Faivre, Christian Cognard, Jocelyn Bescond, Amandine Krzesiak, Hugo Contzler, Nathalie Delpech, Jenny Colas, Clarisse Vandebrouck, Stéphane Sébille, Thierry Ferreira
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (6): dmm043927.
Published: 15 June 2020
... of membrane-anchored proteins. The worldwide spread of the Western diet, which is highly enriched in saturated fats, has been clearly correlated with the emergence of a complex syndrome known as metabolic syndrome (MetS). MetS is defined as a cluster of risk factors for cardiovascular diseases, type 2...
Includes: Supplementary data