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1-4 of 4
Keywords: Cardiomyocytes
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Journal Articles
In collection:
Moving Heart Failure to Heart Success
Giulia L. M. Boezio, Shengnan Zhao, Josephine Gollin, Rashmi Priya, Shivani Mansingh, Stefan Guenther, Nana Fukuda, Felix Gunawan, Didier Y. R. Stainier
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (5): dmm049571.
Published: 19 October 2022
... models exhibited smaller ventricles. We identified the initial cause of this phenotype as defective cardiomyocyte growth, resulting in reduced cell surface and volume. This failure of cardiomyocyte growth was followed by decreased proliferation and increased abluminal extrusion. By temporally...
Includes: Supplementary data
Journal Articles
Lisa Elmén, Claudia B. Volpato, Anaïs Kervadec, Santiago Pineda, Sreehari Kalvakuri, Nakissa N. Alayari, Luisa Foco, Peter P. Pramstaller, Karen Ocorr, Alessandra Rossini, Anthony Cammarato, Alexandre R. Colas, Andrew A. Hicks, Rolf Bodmer
Journal:
Disease Models & Mechanisms
Dis Model Mech (2020) 13 (7): dmm044727.
Published: 20 July 2020
...-mediated knockdown of CCR4-NOT components in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) revealed that silencing CNOT1 and other CCR4-NOT genes reduced their proliferative capacity. Silencing CNOT7 also shortened action potential duration. Furthermore, the cardiac-specific...
Includes: Supplementary data
Journal Articles
In collection:
Moving Heart Failure to Heart Success
Journal:
Disease Models & Mechanisms
Dis Model Mech (2019) 12 (10): dmm040691.
Published: 27 September 2019
... , F. , Walsh , S. , Zupicich , J. , Alkass , K. , Buchholz , B. A. , Druid , H. , et al. ( 2009 ). Evidence for cardiomyocyte renewal in humans . Science 324 , 98 - 102 . 10.1126/science.1164680 Bergmann , O. , Zdunek , S. , Felker , A. , Salehpour...
Journal Articles
Marcela K. Preininger, Rajneesh Jha, Joshua T. Maxwell, Qingling Wu, Monalisa Singh, Bo Wang, Aarti Dalal, Zachary T. Mceachin, Wilfried Rossoll, Chadwick M. Hales, Peter S. Fischbach, Mary B. Wagner, Chunhui Xu
Journal:
Disease Models & Mechanisms
Dis Model Mech (2016) 9 (9): 927–939.
Published: 1 September 2016
... arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT), this treatment is unsuccessful in ∼25% of cases. Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) generated from these patients have potential for use in investigating the phenomenon, but it remains...
Includes: Supplementary data
