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Keywords: Cardiomyocyte turnover
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Journal Articles
Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish
Open AccessLindsay B. Murphy, Adrian Santos-Ledo, Tamilvendhan Dhanaseelan, Lorraine Eley, David Burns, Deborah J. Henderson, Bill Chaudhry
Journal:
Disease Models & Mechanisms
Dis Model Mech (2021) 14 (7): dmm049013.
Published: 22 July 2021
... cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remains constant throughout life but that onset of fibrosis is associated with a late increase in apoptosis. These findings correlate with decreases in voluntary swimming activity, critical swimming speed (Ucrit...