... pathophysiologic pathways in heart failure need to be uncovered. Interrogating mechanisms of regeneration of the myocardium is a major goal of the cardiovascular research community. Importantly, some species have a propensity for cardiac regeneration, and understanding the mechanisms of this phenomenon could...

...Eleanor L. Price; Joaquim M. Vieira; Paul R. Riley ABSTRACT Heart failure is a major cause of death worldwide owing to the inability of the adult human heart to regenerate after a heart attack. However, many vertebrate species are capable of complete cardiac regeneration following injury...