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Keywords: Bulbar dysfunctionClose
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (2): dmm032623.
Published: 26 February 2018
... typically die from an inability to clear the airway. We investigated whether motor neuron degeneration is at the root of bulbar dysfunction by studying SCA1 knock-in ( Atxn1 154Q/+ ) mice. Spinal cord and brainstem motor neurons were assessed in Atxn1 154Q/+ mice at 1, 3 and 6 months of age. Specifically...
Includes: Supplementary data