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Keywords: Bone morphogenetic protein
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Journal Articles
Journal Articles
Dis Model Mech (2020) 13 (9): dmm046441.
Published: 21 September 2020
... I (ACVR1). These mutations cause dysregulated bone morphogenetic protein (BMP) signalling, leading to HO at extraskeletal sites including, but not limited to, muscles, ligaments, tendons and fascia. Ever since the identification of the causative gene, developing a cure for FOP has been a focus...
Journal Articles
Dis Model Mech (2015) 8 (2): 139–146.
Published: 1 February 2015
... that interactions between genes and the environment play a role in the widely variable penetrance and expressivity of HPE, although direct investigation of such effects has been limited. The goal of this study was to examine whether mice carrying a mutation in a gene encoding the bone morphogenetic protein (BMP...
Includes: Supplementary data