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Keywords: BSCL2
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Journal Articles

Ablation of Bscl2 /seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

In collection:
Metabolic Disorders
George D. Mcilroy, Sharon E. Mitchell, Weiping Han, Mirela Delibegović, Justin J. Rochford
Journal: Disease Models & Mechanisms
Dis Model Mech (2020) 13 (1): dmm042655.
https://doi.org/10.1242/dmm.042655
Published: 17 January 2020
...George D. Mcilroy; Sharon E. Mitchell; Weiping Han; Mirela Delibegović; Justin J. Rochford ABSTRACT Mutations affecting the BSCL2 gene cause the most severe form of congenital generalised lipodystrophy (CGL). Affected individuals develop severe metabolic complications including diabetes and hepatic...
View article titled, Ablation of <span class="search-highlight">Bscl2</span> &#x2F;seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy
Open the PDF for Ablation of <span class="search-highlight">Bscl2</span> /seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy in another window
Includes: Supplementary data
Journal Articles

Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ

Guoxi Li, Libin Zhou, Ying Zhu, Conghui Wang, Sha Sha, Xunde Xian, Yong Ji, George Liu, Ling Chen
Journal: Disease Models & Mechanisms
Dis Model Mech (2015) 8 (12): 1615–1624.
https://doi.org/10.1242/dmm.021550
Published: 1 December 2015
...Guoxi Li; Libin Zhou; Ying Zhu; Conghui Wang; Sha Sha; Xunde Xian; Yong Ji; George Liu; Ling Chen ABSTRACT The seipin gene ( BSCL2 ) was originally identified in humans as a loss-of-function gene associated with congenital generalized lipodystrophy type 2 (CGL2). Neuronal seipin-knockout (seipin...
View article titled, Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ
Open the PDF for Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ in another window
Includes: Supplementary data