1-1 of 1
Keywords: Airway resistance
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma

Open Access
Youming Zhang, Thanushiyan Poobalasingam, Laura L. Yates, Simone A. Walker, Martin S. Taylor, Lauren Chessum, Jackie Harrison, Loukia Tsaprouni, Ian M. Adcock, Clare M. Lloyd, William O. Cookson, Miriam F. Moffatt, Charlotte H. Dean
Journal: Disease Models & Mechanisms
Dis Model Mech (2018) 11 (1): dmm031369.
https://doi.org/10.1242/dmm.031369
Published: 29 January 2018
... between wild-type and Dpp10 145D/145D mice. However, after house dust mite (HDM) treatment, Dpp10 mutant mice showed significantly increased airway resistance in response to 100 mg/ml methacholine. Total serum IgE levels and bronchoalveolar lavage (BAL) eosinophil counts were significantly higher...
View article titled, Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma
Open the PDF for Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma in another window
Includes: Supplementary data