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Keywords: Acetylcholine
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Journal Articles
In collection:
C. elegans as a Disease Model
Peter A. Kropp, Philippa Rogers, Sydney E. Kelly, Rebecca McWhirter, Willow D. Goff, Ian M. Levitan, David M. Miller, III, Andy Golden
Journal:
Disease Models & Mechanisms
Dis Model Mech (2023) 16 (2): dmm049594.
Published: 1 February 2023
... elegans strains that recreated patient-specific point variants in the C. elegans ortholog ( nfu-1 ) that result in allele-specific dysfunction. Each of these mutants, Gly147Arg and Gly166Cys, have altered acetylcholine signaling at neuromuscular junctions, but opposite effects on activity and motility. We...
Includes: Supplementary data
