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Keywords: ATP
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Journal Articles
Dis Model Mech (2017) 10 (5): 597–603.
Published: 01 May 2017
.... Several additional signaling molecules are likely to be involved in the activation of the regeneration program in these cells. Using an in vitro cellular model consisting of co-cultured primary neurons and Schwann cells, we found that ATP is released by neurons injured by the anti-GQ1b antibody plus...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2016) 9 (11): 1295–1305.
Published: 01 November 2016
... assumed. Instead, basal mitochondrial respiration and ATP synthesis are dramatically elevated in PD lymphoblasts. The mitochondrial mass, genome copy number and membrane potential were unaltered, but the expression of indicative respiratory complex proteins was also elevated. This explains the increased...
Includes: Supplementary data
Journal Articles
Dis Model Mech (2014) 7 (7): 895–905.
Published: 01 July 2014
... replication stress and DNA damage. Both RP-deficient zebrafish and human hematopoietic cells showed activation of the ATR/ATM-CHK1/CHK2/p53 pathway. Other features of RP deficiency included an imbalanced dNTP pool, ATP depletion and AMPK activation. Replication stress and DNA damage in cultured cells in non...
Includes: Supplementary data