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Keywords: 4-phenylbutyrate
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Journal Articles
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Drug Discovery
Dis Model Mech (2016) 9 (11): 1317–1328.
Published: 1 November 2016
..., each of the four mutant proteins also failed to conduct Cl − ions in transiently transfected cells as determined by whole-cell patch clamp. We demonstrate that a combination of two clinically approved drugs, bortezomib and 4-phenylbutyrate (4PBA), successfully restored the expression and localisation...
Includes: Supplementary data