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Keywords: β-arrestin
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Journal Articles
Jennifer L. Philip, Md. Abdur Razzaque, Mei Han, Jinju Li, Tiju Theccanat, Xianyao Xu, Shahab A. Akhter
Journal:
Disease Models & Mechanisms
Dis Model Mech (2015) 8 (12): 1579–1589.
Published: 1 December 2015
... oxidase 4 (Nox4) is a major source of cardiac reactive oxygen species (ROS); however, mechanisms of Nox4 regulation are unclear. β-arrestins are scaffold proteins that signal in G-protein-dependent and -independent pathways; for example, in ERK activation. We hypothesize that β-arrestins regulate...