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Robert K. Semple
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Journal Articles

Female Alms1-deficient mice develop echocardiographic features of adult but not infantile Alström syndrome cardiomyopathy

Open Access
In collection:
Rare Disease Translational Research
Eleanor J. McKay, Ineke Luijten, Sophie Broadway-Stringer, Adrian Thomson, Xiong Weng, Katya Gehmlich, Gillian A. Gray, Robert K. Semple
Journal: Disease Models & Mechanisms
Dis Model Mech (2024) 17 (6): dmm050561.
https://doi.org/10.1242/dmm.050561
Published: 28 June 2024
View articletitled, Female Alms1-deficient mice develop echocardiographic features of adult but not infantile Alström syndrome cardiomyopathy
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Includes: Supplementary data
Journal Articles

Insulin at 100 years – is rebalancing its action key to fighting obesity-related disease?

Open Access
Gemma V. Brierley, Robert K. Semple
Journal: Disease Models & Mechanisms
Dis Model Mech (2021) 14 (11): dmm049340.
https://doi.org/10.1242/dmm.049340
Published: 29 November 2021
View articletitled, Insulin at 100 years – is rebalancing its action key to fighting obesity-related disease?
Open the PDF for Insulin at 100 years – is rebalancing its action key to fighting obesity-related disease? in another window
Journal Articles

NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CA H1047R homozygosity in pluripotent stem cells

Open Access
In collection:
Advanced in vitro models
Ralitsa R. Madsen, James Longden, Rachel G. Knox, Xavier Robin, Franziska Völlmy, Kenneth G. Macleod, Larissa S. Moniz, Neil O. Carragher, Rune Linding, Bart Vanhaesebroeck, Robert K. Semple
Journal: Disease Models & Mechanisms
Dis Model Mech (2021) 14 (3): dmm048298.
https://doi.org/10.1242/dmm.048298
Published: 11 March 2021
View articletitled, NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CA H1047R homozygosity in pluripotent stem cells
Open the PDF for NODAL/TGFβ signalling mediates the self-sustained stemness induced by PIK3CA H1047R homozygosity in pluripotent stem cells in another window
Includes: Supplementary data
Journal Articles

Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model

Open Access
In collection:
Metabolic Disorders
Jian-Hua Chen, Kim Jee Goh, Nuno Rocha, Matthijs P. Groeneveld, Marina Minic, Timothy G. Barrett, David Savage, Robert K. Semple
Journal: Disease Models & Mechanisms
Dis Model Mech (2017) 10 (12): 1411–1420.
https://doi.org/10.1242/dmm.030981
Published: 1 December 2017
View articletitled, Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model
Open the PDF for Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model in another window
Includes: Supplementary data