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Cover: Courtesy of Christopher M. Dooley, Wellcome Trust Sanger Institute. - PDF Icon PDF LinkTable of contents
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EDITORIAL
A MODEL FOR LIFE
From fish tank to bedside in cancer therapy: an interview with Leonard Zon
Leonard Zon, who is based at Harvard Medical School, is internationally recognized for his pioneering work in hematology and stem cell biology. His lab uses zebrafish as a model to understand blood cell development and, in recent years, has made inspiring breakthroughs in the treatment of blood diseases and cancer, helping to establish zebrafish as a powerful model for translational research. In this interview, Leonard speaks to Disease Models & Mechanisms Editor-in-Chief, Ross Cagan, about the evolution of his career from developmental biologist to physician-scientist and the stories behind some of his major research accomplishments. He also discusses challenges and opportunities in zebrafish research and provides advice on translating basic research findings to the clinic.
AT A GLANCE
REVIEWS
RESEARCH ARTICLES
Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation
RESOURCE ARTICLES
DMM Journal Meeting 2024: Pre-clinical Modelling of Human Genetic Disease and Therapy

Registration is open for our 2024 Journal Meeting. Rapid advances in gene editing and genetic technologies have revolutionised our ability to model human genetic disease and provided new hope for gene therapies. At this Meeting, speakers will present the very latest advances in modelling human genetic disease.
Moving towards heart success – Disease Models & Mechanisms Special Issue

DMM's most recent special issue compiles articles that investigate the genetic and biological mechanisms of heart failure and identify potential therapeutic strategies.
Sustainable Conferencing Initiative

Through our Sustainable Conferencing Grants, we promote the use of new technology and greener modes of travel. Our blog posts showcase examples of sustainability in action and share guidance about how new technologies and different conference formats work in practice.