Issues
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Cover image
Cover Image
Cover: High-resolution mapping of the fiber architecture of the mouse brain in vivo. Structural details of the wild-type (top image) and Toxoplasma gondii-infected (bottom image) C57BL6/c mouse brains are highlighted, using diffusion-based global fiber tracking. Note the subtle changes in the cortical connectivity pattern and the loss of fiber density in the infected brain. The local fiber orientation is colour-coded: red, medio-lateral; green, dorso-ventral; blue, rostro-caudal. See article by Parlog et al. on page 459. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
CLINICAL PUZZLE
REVIEW
RESEARCH ARTICLES
DMM Journal Meeting 2024: Pre-clinical Modelling of Human Genetic Disease and Therapy

Registration is now open for our 2024 Journal Meeting. Rapid advances in gene editing and genetic technologies have revolutionised our ability to model human genetic disease and provided new hope for gene therapies. At this Meeting, we will present the very latest advances in modelling human genetic disease.
Moving towards heart success – Disease Models & Mechanisms Special Issue

DMM's most recent special issue compiles articles that aim to move heart failure to heart success by fundamentally addressing the roots of failure to identify curative strategies.
Crossroads in Virology

Our October Editorial written by Sumana Sanyal emphasises the urgency of a concerted effort in understanding virus–host interactions to inform the development of therapeutics and vaccines, helping to predict disease outcomes. Read the full Editorial here.
A Model for Life - an interview with Professor Kiran Musunuru




Read our new A Model for Life interview with Kiran Musunuru. Prof Musunuru investigates the mechanisms of disease in model systems, with the ultimate goal of developing innovative gene editing therapies.
Sustainable Conferencing Initiative

Through our Sustainable Conferencing Grants, we promote the use of new technology and greener modes of travel. Our blog posts showcase examples of sustainability in action and share experience about how new technologies and conference formats work in practice.