Issues
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Cover image
Cover Image
Cover: Staining for DNA damage in sections from prostate cancer xenograft tumours, showing immunostaining of γH2AX (red fluorescence) and overlay with DAPI as a counterstain (blue fluorescence). Strong labeling was seen with the different treatments, including with the combined treatment of ultrasound-stimulated microbubbles combined with high radiation (MB+US+8Gy), shown here. See article by Al-Mahrouki et al. on page 363. - PDF Icon PDF LinkTable of contents
In This Issue
Community News
A Model For Life
Revolutionizing cancer care with next-generation sequencing: an interview with Elaine Mardis
Elaine Mardis, co-director at the Washington University Genome Institute, has a long-standing interest in the development of sequencing technologies, which, in the 1990s, led her to play a pivotal role in the completion of the Human Genome project. Driven by the desire to apply her technological know-how to the improvement of human health, she then pioneered the sequencing and analysis of cancer genomes. These milestones have established Elaine as a leader in the cancer genomics field. In this interview, she recalls the events that shaped her career path, discusses the value of industry experience in a research setting, and provides her perspectives on challenges to clinical implementation of next-generation sequencing.
Reviews
Research Articles
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells
Resource Articles
Correction
History of our journals
As our publisher, The Company of Biologists, turns 100 years old, read about DMM’s history and explore the journey of each of our sister journals: Development, Journal of Cell Science, Journal of Experimental Biology and Biology Open.
A new perspective on disease research
DMM publishes perspectives – peer-reviewed articles that provide expert analysis of a topic important to the disease research community. Read our collection from authors presenting new or potentially controversial ideas or hypotheses, to help address future challenges and forge new directions.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
