Issues
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Cover image
Cover Image
Cover: Immunocytochemistry image of an in vitro model of human neocortical development using human pluripotent stem cells. Neocortical neurons are immunostained to show TUJ1 (green) and proliferating progenitor cells are immunostained to show Ki67 (red). Structures that retain essential features of human neocortical development formed after neuroepithelial rosettes were seeded and cultured in the presence of neocortical trophic factors. This model is amenable to drug screening and can be employed to identify strategies for preventing or ameliorating conditions of developmental injury to the human cerebral cortex. See article by Kindberg et al. on page 1397. - PDF Icon PDF LinkTable of contents
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IN THIS ISSUE
A MODEL FOR LIFE
‘Back and forth’ from models to patients to understand kidney disease: an interview with Katalin Susztak
Katalin Susztak is currently Associate Professor at Perelman School of Medicine at the University of Pennsylvania, where she conducts research on chronic and diabetic kidney disease. After her medical studies, her science career began by investigating ion-channel regulation and function at Semmelweis University, in Budapest. She then moved to the United States, where, thanks to the fortunate encounter with her future mentor, Erwin Böttinger, she worked as a research fellow in the Renal Division of the Albert Einstein College of Medicine in New York. Since then, she has successfully kept pursuing her career in the field of kidney research. The innovative approach of Katalin’s lab is to combine efficient high-throughput analysis of patient samples with mechanistic approaches in animal models, in order to advance our understanding of kidney disease mechanisms and identify new therapeutic targets. In this interview, Katalin travels through her career, from her first steps into biophysics, to her residency and finally to her established position as a kidney-specialist scientist, discussing exciting aspects of her work and current challenges in her field.
REVIEW
RESEARCH ARTICLES
Triptolide treatment reduces Alzheimer’s disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD
RESOURCE ARTICLES
History of our journals

As our publisher, The Company of Biologists, turns 100 years old, read about DMM’s history and explore the journey of each of our sister journals: Development, Journal of Cell Science, Journal of Experimental Biology and Biology Open.
A new perspective on disease research
DMM publishes perspectives – peer-reviewed articles that provide expert analysis of a topic important to the disease research community. Read our collection from authors presenting new or potentially controversial ideas or hypotheses, to help address future challenges and forge new directions.
Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.