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November 2014
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Cover image
Cover Image
Cover: Macro image of an individual Drosophila melanogaster used for in vivo high-throughput screening in myotonic dystrophy type 1 (DM1). This fly model does not display eye-observable disease phenotypes but combines simultaneous expression of the disease-causing mutation and a luciferase-reporter system, which allows the reliable quantification of a DM1-linked differential splicing event (spliceosensor flies). These reporter-based flies launched a novel in vivo drug-discovery assay from well-established in vitro approaches, and allowed fast large-scale chemical screening using Drosophila melanogaster. Image kindly provided by Dr Arturo López Castel. See article by García-Alcover et al. on page 1297. - PDF Icon PDF LinkTable of contents
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ISSN 1754-8403
EISSN 1754-8411
History of our journals
As our publisher, The Company of Biologists, turns 100 years old, read about DMM’s history and explore the journey of each of our sister journals: Development, Journal of Cell Science, Journal of Experimental Biology and Biology Open.
A new perspective on disease research
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
