Issues
-
Cover image
Cover Image
Cover: Coloured electron micrograph of a dystrophic neurite in a central brain neuron of aged D. melanogaster. Note the accumulation of multilamellar and multivesicular bodies. Aging increases both the number and size of autophagic organelles, with the largest ones reaching up to 2 µm in diameter. Inactivation of Cdk5-p35 kinase caused this increase to occur precociously, and resulted in increased final numbers of such organelles. Dotted orange line outlines the neurite perimeter. See article by Trunova and Giniger on page 210. - PDF Icon PDF LinkTable of contents
In This Issue
Research Highlights
A Model For Life
Linking genetics with biology in disease research: an interview with Nick Hastie
Professor Nick Hastie is Director of the MRC Human Genetics Unit in Edinburgh, a centre originally famous for early studies of chromosome biology. He is also Director of the newly formed Institute of Genetics and Molecular Medicine, which includes the Human Genetics Unit. In addition to overseeing the work on cancer and developmental genetics in his own lab, he is involved in a number of large-scale genetic studies aimed at uncovering genetic risk factors for various human diseases.
Commentary
Perspective
Podcast
Research Articles
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
Resource Article
History of our journals
As our publisher, The Company of Biologists, turns 100 years old, read about DMM’s history and explore the journey of each of our sister journals: Development, Journal of Cell Science, Journal of Experimental Biology and Biology Open.
A new perspective on disease research
DMM publishes perspectives – peer-reviewed articles that provide expert analysis of a topic important to the disease research community. Read our collection from authors presenting new or potentially controversial ideas or hypotheses, to help address future challenges and forge new directions.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
