Issues
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Cover image
Cover Image
Cover: Micro-computed tomography images of the spines and ribs of control (left) and induced SHP-2-deficient (right) adult mice. SHP-2-deficient mice show spinal curvature (kyphosis and scoliosis), osteopetrosis and ectopic calcified growths. The induced SHP-2-deficient mouse serves as a useful model for understanding how mutations of the PTPN11 gene (which encodes SHP-2) cause skeletal malformations in humans. See article by Bauler et al. on page 228. 2 2 - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
EDITORIAL
JOURNAL CLUB
A MODEL FOR LIFE
Translating metabolic biochemistry into the clinic: an interview with Steve O’Rahilly
Professor Steve O’Rahilly is one of the UK’s most renowned clinical researchers. He made his reputation by combining clinical practice with scientific and clinical studies focused on understanding the causes and consequences of obesity and insulin resistance. Here, he talks about his research philosophy, and his wider role as a spokesman for obesity research.
CLINICAL PUZZLE
COMMENTARY
PERSPECTIVE
RESEARCH ARTICLE
RESOURCE ARTICLE
Call for Papers – Infectious Disease: Evolution, Mechanisms and Global Health
Showcase your latest research on our upcoming Special Issue: Infectious Disease: Evolution, Mechanisms and Global Health. This issue will be coordinated by DMM Editors Sumana Sanyal and David Tobin alongside Guest Editors Judi Allen and Russell Vance. The deadline for submitting articles to this Special Issue has been extended to Monday 24 February 2025.
Biologists @ 100 - join us in Liverpool in March 2025
We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate a DMM programme on antimicrobial resistance on 26 March 2025. Find out more and register to join us in March 2025 in Liverpool, UK.
Apply to become a reporter at the Biologists @ 100 conference
Are you keen to get more science communication experience? Is your research related to developmental and stem cell biology or microscopy? The Node and FocalPlane are looking for one reporter each to attend and report from the Biologists @ 100 conference, happening on 24-27 March 2025 in Liverpool, UK. Apply by 29 November 2024.
The role of the International Society for Stem Cell Research guidelines in disease modelling
The International Society for Stem Cell Research (ISSCR) provides comprehensive guidelines and standards for using human stem cells in biomedical research. In this Editorial, Cody Juguilon and Joseph Wu discuss how and why these should be incorporated in disease modelling research.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.