Issues
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Cover image
Cover Image
Cover: Depolarisation of transmembrane potential in a select group of 'instructor cells' triggers a profoundly hyperpigmented phenotype in Xenopus laevis tadpoles (shown in the figure) owing to a neoplastic-like conversion of melanocytes. When activated by a serotonergic signal from the depolarised instructor cells, melanocytes overproliferate, acquire a highly dendritic morphology, and aggressively colonise organs and blood vessels throughout the animal. See article by Blackiston et al. on page 67. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
EDITORIAL
JOURNAL CLUB
A MODEL FOR LIFE
At the leading edge of cancer research: an interview with Joan Brugge
Joan Brugge has been an innovator in cancer research since the beginning of her career, when she isolated the viral and cellular forms of the Src protein as a postdoctoral fellow at the University of Colorado. In this interview, she describes the exciting sequence of events that opened up the field during this time, and discusses why a career in cancer research is still such an inspiring path to follow today.
PRIMER
PERSPECTIVE
RESEARCH ARTICLE
Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome
PEX13 deficiency in mouse brain as a model of Zellweger syndrome: abnormal cerebellum formation, reactive gliosis and oxidative stress
RESEARCH REPORT
The Company of Biologists Workshops

For the last 15 years, our publisher, The Company of Biologists, has provided an apt environment to inspire biology and support biologists through our Workshops series. Read about the evolution of the Workshop series and revisit JEB's experience with hosting the first Global South Workshop.
A new perspective on disease research
DMM publishes perspectives – peer-reviewed articles that provide expert analysis of a topic important to the disease research community. Read our collection from authors presenting new or potentially controversial ideas or hypotheses, to help address future challenges and forge new directions.
Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
Fast & Fair peer review

Our sister journal Biology Open has recently launched the next phase of their Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. To learn more about BiO’s progress and future plans, read the Editorial by Daniel Gorelick, or visit the Fast & Fair peer review page.
Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and Sadaf Farooqi, and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.