Issues
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Cover image
Cover Image
Confocal projection of a vibratome cross-section through the head of a 7 days post-fertilization zebrafish larva that is mutant in the von Hippel-Lindau (vhl) tumor suppressor gene. Blood vessels are labeled in green. TG(kdr-like:egfp) vhl mutants develop pronounced neovascularization of the brain and eyes. Fluorescent angiography with a 2,000,000 molecular weight rhodamine-dextran conjugate (red), which is normally too large to pass through the vessel wall, reveals severe vascular leakage in vhl mutants at 20-25 hours post-injection. In the vhl−/− eye this leads to the formation of macular edema (red patches), similar to human angiogenic retinopathies. See research article by van Rooijen et al. on page 343. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
JOURNAL CLUB
EDITORIAL
COMMUNITY NEWS
A MODEL FOR LIFE
Funding scientific discovery: an interview with Sir Mark Walport
Sir Mark Walport is Director of the Wellcome Trust, one of the world’s largest funders of scientific research. Here he talks about the qualities of a successful scientist and how informatics might advance the future of medicine.
CLINICAL PUZZLE
PRIMER
SPECIAL ARTICLE
COMMENTARY
PERSPECTIVE
RESEARCH ARTICLE
Stromal regulation of vessel stability by MMP14 and TGFβ
Interviews with Biologists @ 100 conference speakers

Explore our interviews with keynote speakers from the Biologists @ 100 conference, hosted to celebrate our publisher’s 100th anniversary, where we discuss climate change and biodiversity with Hans-Otto Pörtner and Jane Francis, health and disease with Charles Swanton and Sadaf Farooqi, and emerging technologies with Manu Prakash and Jennifer Lippincott-Schwartz.
A new perspective on disease research
DMM publishes perspectives – peer-reviewed articles that provide expert analysis of a topic important to the disease research community. Read our collection from authors presenting new or potentially controversial ideas or hypotheses, to help address future challenges and forge new directions.
Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
Fast & Fair peer review

Our sister journal Biology Open has recently launched the next phase of their Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. To learn more about BiO’s progress and future plans, read the Editorial by Daniel Gorelick, or visit the Fast & Fair peer review page.
History of our journals

As our publisher, The Company of Biologists, turns 100 years old, read about DMM’s history and explore the journey of each of our sister journals: Development, Journal of Cell Science, Journal of Experimental Biology and Biology Open.