Issues
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Cover image
Cover Image
Cover: Image of a Drosophila central nervous system from a third-instar larva. The tissue contains numerous neural progenitor clones that are mutant for the coenzyme Q10 biosynthetic gene qless, marked with nuclear GFP (green). Also shown are the primary neural progenitors themselves, called neuroblasts (red). Loss of qless activity produces a variety of undersized clones with neuroblasts tending to be absent from the smallest ones. See Research Report by Grant et al. on page 799. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
JOURNAL CLUB
COMMUNITY NEWS
A MODEL FOR LIFE
Targeting cancer: an interview with Tyler Jacks
Tyler Jacks is one of the world’s foremost experts on mouse models of cancer and has pioneered the use of gene targeting in the mouse to construct more accurate pre-clinical models. Here, he discusses his early influences and motivation, and his hopes for the future of cancer research.
BOOK & ART REVIEW
CLINICAL PUZZLE
PRIMER
COMMENTARY
PERSPECTIVE
RESEARCH ARTICLE
Disease-specific, neurosphere-derived cells as models for brain disorders
RESEARCH REPORT
DMM Journal Meeting 2024: Pre-clinical Modelling of Human Genetic Disease and Therapy
Registration is now open for our 2024 Journal Meeting. Rapid advances in gene editing and genetic technologies have revolutionised our ability to model human genetic disease and provided new hope for gene therapies. At this Meeting, we will present the very latest advances in modelling human genetic disease.
A new call for papers is underway
Showcase your latest research in our upcoming special issue Translating Multiscale Research in Rare Disease, coordinated by DMM Editors Monica Justice, Karen Liu and Monkol Lek, and Guest Editor Kate Rauen. The deadline for submitting articles to the special issue is Monday 6 November 2023.
Moving towards heart success – Disease Models & Mechanisms Special Issue
DMM's most recent special issue compiles articles that aim to move heart failure to heart success by fundamentally addressing the roots of failure to identify curative strategies.
Adult zebrafish as advanced models of human disease
Editor-in-Chief Liz Patton and Editorial Board member Rich White discuss the unique advantages of adult zebrafish for studying human disease biology. Read the Open Access Editorial here.
The Forest of Biologists
The Forest of Biologists is a biodiversity initiative created by The Company of Biologists, with support from the Woodland Trust. For every Research and Review article published in Disease Models & Mechanisms a native tree is planted in a UK forest. In addition to this we are protecting and restoring ancient woodland and are dedicating these trees to our peer reviewers. Visit our virtual forest to learn more.
