Issues
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Cover image
Cover Image
Mitochondria and Legionella infections in the social amoeba. The image shows multicellular fruiting bodies (gold) of the social amoeba or cellular slime mould, Dictyostelium discoideum. The fruiting bodies are 1-2 mm high. The rough outline of a single amoeba (magenta) encloses mitochondria (green, GFP fluorescence) and four Legionella pneumophila (red, DsRed fluorescence) that have infected the cell. The diameter of the cell is approximately 12 μm. In this issue of DMM, Francione et al. report that chronic AMPK signaling causes mitochondrially diseased Dictyostelium cells to support intracellular Legionella proliferation better than wild-type cells. Image by P. R. Fisher and P. E. Taylor. See research article on page 479. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
JOURNAL CLUB
EDITORIAL
COMMUNITY NEWS
A MODEL FOR LIFE
Taking translational research to heart: an interview with Sir Magdi Yacoub
Sir Magdi Yacoub is a founding editor of DMM, whose work as a cardiac surgeon and researcher has devised new operations for congenital and acquired heart disease, and has advanced heart and heart-lung transplantation techniques. He and his collaborators have studied the sophisticated functions of living heart valves and are using stem cells to produce a tissue-engineered valve that can reproduce their functions. Here, he discusses with fellow DMM founding editor Nadia Rosenthal, how his career evolved and why he hopes research will put heart surgeons like himself out of business.
CLINICAL PUZZLE
PRIMER
PERSPECTIVE
RESEARCH ARTICLE
RESOURCE ARTICLE
ERRATUM
Call for papers – In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery

We invite you to submit your latest research to our upcoming special issue: In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery, coordinated by DMM Editor Vivian Li (The Francis Crick Institute, London, UK), alongside Guest Editors Austin Smith (University of Exeter, UK) and Joseph Wu (Stanford University School of Medicine, USA).The deadline for submitting articles is 6 October 2025.
The Company of Biologists Workshops

For the last 15 years, our publisher, The Company of Biologists, has provided an apt environment to inspire biology and support biologists through our Workshops series. Read about the evolution of the Workshop series and revisit JEB's experience with hosting the first Global South Workshop.
Read & Publish Open Access publishing: what authors say

We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
Fast & Fair peer review

Our sister journal Biology Open has recently launched the next phase of their Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. To learn more about BiO’s progress and future plans, read the Editorial by Daniel Gorelick, or visit the Fast & Fair peer review page.
Propose a new Workshop for 2027

We are currently seeking proposals for Workshops to be held in 2027. As one of the scientific organisers of a The Company of Biologists Workshop, your involvement will be focused on interdisciplinary, cutting-edge science and promoting new partnerships and collaborations. We focus on the logistics. Are you thinking about proposing a topic for one of our Workshops? Apply by Friday 30 May 2025.