Issues
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A girl with Wolf-Hirschhorn syndrome (WHS) is holding a mouse, reflecting the significant biological relationship between the two species whereby mice can serve as a model system to study human disease. Mice that are homozygous for a null allele of the fibroblast growth factor receptor-like 1 (Fgfrl1) gene recapitulate multiple aspects of WHS, including skeletal malformations and cardiac valve defects. See research article by Catela et al. on page 283.Close Modal - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
JOURNAL CLUB
EDITORIAL
COMMUNITY NEWS
A MODEL FOR LIFE
Using zebrafish to understand the genome: an interview with Nancy Hopkins
Nancy Hopkins is famous for pushing the envelope: both in her pursuit to understand cancer genetics and in exposing professional disparities between men and women. Here, she discusses influential moments that have defined her career path, and her concerns for the future.
CLINICAL PUZZLE
PRIMER
AT A GLANCE
PERSPECTIVE
RESEARCH ARTICLE
RESEARCH REPORT
Virtual Meeting - Developmental Disorders: From Mechanism to Treatment
A collaboration between the Development and Disease Models & Mechanisms journal teams, this virtual Meeting will unite developmental biologists, human geneticists and clinical researchers to focus on building bridges from bench to clinic. Register your interest and find out more.
High-dose vitamin B1 therapy prevents the development of experimental fatty liver driven by overnutrition
Vitamin B1 is shown to prevent nutrition-induced fatty liver in our current Editor’s choice by Hay Davir and his colleagues, when they use sheep as a large-animal model for studying the disease.
Find out more in an interview with the paper's first authors, Mugagga Kalyesubula and Ramgopal Mopuri.
Upcoming grant deadlines
Grants awarded by The Company of Biologists help scientists travel, attend events and host sustainable activities. Make a note of the upcoming application deadlines and find out more about the grants on offer:
DMM Conference Travel Grants
17 May 2021
Sustainable Conferencing Grants
17 May 2021
Travelling Fellowships
31 May 2021
Scientific Meeting Grants
4 June 2021
Call for papers - The RAS Pathway: Diseases, Therapeutics and Beyond
Our upcoming special issue is welcoming submissions until 3 May 2021. Guest-edited by Donita Brady (Perelman School of Medicine at the University of Pennsylvania, USA) and Arvin Dar (Icahn School of Medicine at Mount Sinai, USA), the issue will focus on targeting the RAS pathway.
