Issues
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Cover image
Cover Image
Representative images of tail skin pigmentation in wild-type, p53−/−, K5TRF2 and p53−/−K5TRF2 mice at 8 weeks of age. See research article by Stout and Blasco on page 139.
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IN THIS ISSUE
RESEARCH HIGHLIGHT
EDITORIAL
Courting change
In scientific communication, the long tail has not yet appeared. Why not?
Drinking from the firehose of scientific publishing
The fundamental question is this: can the wisdom of crowds be exploited to post-filter the literature?
Disease models and mechanisms in the classroom
At the University of Pennsylvania (PENN), we devote an entire graduate-level course to the study of human disease models: Seminar on Current Genetic Research: Modeling Human Disease in Diverse Genetic Systems
Visualizing anti-tumor immune responses in vivo
Real-time imaging of stromal and immune cells in tumors is an emerging field that will greatly help us to understand the role of these non-malignant tumor components in tumor progression and therapy
COMMUNITY NEWS
A MODEL FOR LIFE
The cell cycle and beyond: an interview with Paul Nurse
Sir Paul Nurse is a recipient of the 2001 Nobel Prize in Medicine for his work on one of the key regulators of the cell cycle, CDK (cyclin-dependent kinase). In this interview with Jim Smith, he discusses his choice of model organism, scientific leadership and the early influences on his career.
CLINICAL PUZZLE
COMMENTARY
PERSPECTIVE
RESEARCH ARTICLE
Tissue-specific conditional CCM2 knockout mice establish the essential role of endothelial CCM2 in angiogenesis: implications for human cerebral cavernous malformations
RESEARCH REPORT
History of our journals
As our publisher, The Company of Biologists, turns 100 years old, read about DMM’s history and explore the journey of each of our sister journals: Development, Journal of Cell Science, Journal of Experimental Biology and Biology Open.
A new perspective on disease research
DMM publishes perspectives – peer-reviewed articles that provide expert analysis of a topic important to the disease research community. Read our collection from authors presenting new or potentially controversial ideas or hypotheses, to help address future challenges and forge new directions.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.
