Issues
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Cover image
Cover Image
Two 54-hour-old zebrafish embryos that were injected with 3000 dsRed-expressing E. coli at the age of 30 hours. The bacteria have spread throughout the body, but healthy fish will eventually eliminate them through innate immune mechanisms. If gamma interferon signalling is compromised, the fish is no longer able to eliminate the bacteria. See research article by Sieger et al. on page 571. - PDF Icon PDF LinkTable of contents
IN THIS ISSUE
RESEARCH HIGHLIGHT
JOURNAL CLUB
EDITORIAL
COMMUNITY NEWS
A MODEL FOR LIFE
Telomeres and Tetrahymena: an interview with Elizabeth Blackburn
Elizabeth Blackburn knows that loose ends contribute to aging and many of its associated diseases. She, together with Carol Greider and Jack Szostak, received the 2009 Nobel Prize in Physiology or Medicine for their work on the synthesis and function of telomeres, the unusual DNA sequences at the ends of chromosomes. Telomere changes are now recognized in human diseases ranging from cancer and cardiovascular disease to depression. Here, she discusses her approach to mentorship, how scientists might inform public policy, and new directions in telomere research.
BOOK & ART REVIEW
PRIMER
COMMENTARY
PERSPECTIVE
RESEARCH ARTICLE
RESEARCH REPORT
DMM Journal Meeting 2024: Pre-clinical Modelling of Human Genetic Disease and Therapy
Registration is now open for our 2024 Journal Meeting. Rapid advances in gene editing and genetic technologies have revolutionised our ability to model human genetic disease and provided new hope for gene therapies. At this Meeting, we will present the very latest advances in modelling human genetic disease.
A new call for papers is underway
Showcase your latest research in our upcoming special issue Translating Multiscale Research in Rare Disease, coordinated by DMM Editors Monica Justice, Karen Liu and Monkol Lek, and Guest Editor Kate Rauen. The deadline for submitting articles to the special issue is Monday 6 November 2023.
Moving towards heart success – Disease Models & Mechanisms Special Issue
DMM's most recent special issue compiles articles that aim to move heart failure to heart success by fundamentally addressing the roots of failure to identify curative strategies.
Adult zebrafish as advanced models of human disease
Editor-in-Chief Liz Patton and Editorial Board member Rich White discuss the unique advantages of adult zebrafish for studying human disease biology. Read the Open Access Editorial here.
The Forest of Biologists
The Forest of Biologists is a biodiversity initiative created by The Company of Biologists, with support from the Woodland Trust. For every Research and Review article published in Disease Models & Mechanisms a native tree is planted in a UK forest. In addition to this we are protecting and restoring ancient woodland and are dedicating these trees to our peer reviewers. Visit our virtual forest to learn more.
