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RESEARCH ARTICLES

Summary: Gata6 haploinsufficiency causes bicuspid aortic valve and congenital heart defects associated with reduced second heart field progenitor differentiation, proliferation and migration, impaired endocardial cushion development and deficient CXCR7 signaling.

Summary: An intrinsically hybrid epithelial/mesenchymal phenotype confers dynamic remodeling of cell-cell junctions and an E-cadherin-indifferent metastatic capacity to the 4T1 model of stage IV breast cancer.

Summary: Drosophila eEF1α2, a well-characterized translation elongation factor, is required for age-related muscle fiber homeostasis, possibly independent of its role in protein synthesis.

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