Issues
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EDITOR'S CHOICE
RESEARCH ARTICLES
Stat3 mediates Fyn kinase-driven dopaminergic neurodegeneration and microglia activation
Summary: This study describes a novel in vivo zebrafish model of neural Fyn kinase activation and identifies Stat3 signaling as a downstream Fyn effector in dopaminergic neuron degeneration and neuroinflammation.
Generation of a zebrafish neurofibromatosis model via inducible knockout of nf2a/b
Editor's choice: Zebrafish nf2a/b genes are expressed in tissues involved in neurofibromatosis type II (NF-2). Inducible knockout of nf2a/b triggers the development of a spectrum of tumors, mirroring the manifestations observed in patients with NF-2.
Modelling quiescence exit of neural stem cells reveals a FOXG1-FOXO6 axis
Summary: This study finds a pro-oncogenic role for FOXO6, downstream of glioblastoma-associated elevated FOXG1, in controlling quiescence exit of mouse neural stem cells.
FIRST PERSON
Call for Papers – Infectious Disease: Evolution, Mechanisms and Global Health
Showcase your latest research on our upcoming Special Issue: Infectious Disease: Evolution, Mechanisms and Global Health. This issue will be coordinated by DMM Editors Sumana Sanyal and David Tobin alongside Guest Editors Judi Allen and Russell Vance. The deadline for submitting articles to this Special Issue has been extended to Monday 24 February 2025.
Biologists @ 100 - join us in Liverpool in March 2025
We are excited to invite you to a unique scientific conference, celebrating the 100-year anniversary of The Company of Biologists, and bringing together our different communities. The conference will incorporate a DMM programme on antimicrobial resistance on 26 March 2025. Find out more and register to join us in March 2025 in Liverpool, UK.
The role of the International Society for Stem Cell Research guidelines in disease modelling
The International Society for Stem Cell Research (ISSCR) provides comprehensive guidelines and standards for using human stem cells in biomedical research. In this Editorial, Cody Juguilon and Joseph Wu discuss how and why these should be incorporated in disease modelling research.
Read & Publish Open Access publishing: what authors say
We have had great feedback from authors who have benefitted from our Read & Publish agreement with their institution and have been able to publish Open Access with us without paying an APC. Read what they had to say.