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SPECIAL ARTICLE

Summary: We summarize the consensus guidelines on the construct validity of rodent models of restless legs syndrome, which have been recently established by a task force of the International Restless Legs Syndrome Study Group.

RESEARCH ARTICLE

Summary: In a mouse model of spinocerebellar ataxia type 3 (SCA3), aberrant cerebellar physiology is apparent early in disease, prior to cerebellar neuronal pathology. Aberrant cerebellar output could be a therapeutic target in SCA3.

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